Wednesday, July 1, 2009

WinNonlin® 6.0

Phoenix™ WinNonlin® 6.0 — Next Generation of the Industry Standard for PK/PD Modeling and NCA

Phoenix WinNonlin improves scientific productivity during critical drug development tasks by providing a comprehensive analysis environment that implements efficient reusable workflows and high quality outputs while reducing barriers to learning and collaboration, enabling more impactful quantitative decision making.
Phoenix WinNonlin 6.0 offers the following benefits:
  • Comprehensive Analysis Environment: Perform virtually all of the analyses for standard PK and PK/PD studies. MORE
  • Efficient Workflow Management: Create, reuse, and share analyses as stored workflows. Easily process, visualize, and tabulate data while allowing the flexibility to edit in Excel. MORE
  • High Quality Outputs: Generate high-quality graphs, tables, and figures allowing for integrated communication of analysis results. MORE
  • Easy to Learn and Share: Minimize the amount of time spent learning the software and promote collaboration through easily transferable project files, workflows, and templates. MORE
  • Enables Compliance: Provide technical controls for 21 CFR Part 11 compliance when used in conjunction with Pharsight Knowledgebase Server™. MORE

Phoenix™ WinNonlin® Features

Key features of Phoenix WinNonlin include the following:

  • Comprehensive Analysis Environment

Perform noncompartmental analysis of both blood and urine data using methods for rich or sparse datasets in a single run.

Three methods of AUC calculation: linear trapezoidal, linear/log trapezoidal, and linear up/log down.

Descriptive statistics, including weighted descriptive statistics.

Units definition and conversions, including the ability to specify preferred output units, units for a dosing regimen, and unit conversions.

Powerful data management tools allow users to append worksheets, change properties and/or transform columns, add BQL Rules or map cross product worksheets, as well as filter, join, merge, pivot, rank, split, and stack data.

Toolbox functions for deconvolution, semicompartmental modeling, nonparametric superposition and crossover design.

Automatic determination of initial estimates.

Analysis using general linear modeling approaches, including bioequivalence tests as appropriate.

Built-in scripting language (Pharsight Modeling Language or PML).

  • Efficient Workflow Management

Workflow management tools that enable users to create, reuse, and share models and projects.

More powerful data management tools. Excel compatible workbooks, including formulas, functions, data import/export, missing value codes, sort, transformations and worksheet merge.

Insert favorite workflow components and/or sub-workflows into larger workflow diagrams.
Easily map data inputs to multiple models.

  • High Quality Outputs

Significantly improved, report-ready graphs, plots, tables and listings greatly reduce the reliance on external graphics software.

Easily insert bar, column, and box plots; histograms; XY, QQ plots, and/or scatter plot matrices into your workflows.

Easily change the formatting of any plot to suit reporting requirements.

One-click export of results, plots, and tables to Microsoft Excel® or Word®, SAS, graphic files, or text.

  • Easy to Learn and Share

An intuitive user interface provides multiple click-paths to accomplish the same tasks, allowing users to use the software in ways that make suit their personal preferences.

All data, models, scripts, tables, BQL rules, documents, models, workflows, plots, graphs, and outputs are contained in one project file that can easily be shared.

Classroom and online training courses will be offered regularly to support new users.

  • Enables Compliance

Every workflow object has a 'Verification' tab that explains whether the object executed properly and any errors that may have occurred.

Full integration with the Pharsight Knowledgebase Server™ (PKS™) data repository enabling all changes to projects to be logged in the PKS database

Validation can be speeded up significantly with the Phoenix Validation Suite™

Note: If anything needed please see the below link-

http://www.pharsight.com/products/prod_phoenix_winnonlin_feature.php

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